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Figure 1 4.1.1 Cardiovascular outcomes in SGLT2 inhibitors: safety studies The EMPA-REG OUTCOME trial, which included 7020 patients with T2DM, was the first to demonstrate the cardiovascular protective effects of empagliflozin (54, 56)

Aerobic activity alone has a smaller effect on preserving lean mass during rapid weight reduction [160]

Efpeglenatide and clinical outcomes with and without concomitant sodium-glucose co-transporter-2 inhibition use in type 2 diabetes: exploratory analysis of the AMPLITUDE-O trial

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